An important step in developing a robust cleaning and disinfection programme for sterile or low bioburden environments is to make a decision of the laboratory who can perform efficacy testing of your selected biocide products that are for your facility. This presentation will describe the laboratory selection process and critical parameters that are relevant to generating accurate, unbiased, quantitative disinfectant testing that is fit for purpose. The scope of this presentation is cleaning and disinfection programmes of biopharmaceutical, cell and gene therapy, pharmaceutical, medical device, and personal care manufacturing.